李发炎, 郑安瑜, 陈大良, 章迟, 薛恩生. 甲状腺微小癌的早期诊断和治疗(附34例临床分析)[J]. 中国肿瘤临床, 2005, 32(5): 275-281. DOI: 10.3969/j.issn.1000-8179.2005.05.010
引用本文: 李发炎, 郑安瑜, 陈大良, 章迟, 薛恩生. 甲状腺微小癌的早期诊断和治疗(附34例临床分析)[J]. 中国肿瘤临床, 2005, 32(5): 275-281. DOI: 10.3969/j.issn.1000-8179.2005.05.010
Li Fayan, Zheng Anyu, Chen Daliang, Zhang Chi, Xue Ensheng. Thyroid Microcarcinoma: the Early-stage Diagnosis and Treatment[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2005, 32(5): 275-281. DOI: 10.3969/j.issn.1000-8179.2005.05.010
Citation: Li Fayan, Zheng Anyu, Chen Daliang, Zhang Chi, Xue Ensheng. Thyroid Microcarcinoma: the Early-stage Diagnosis and Treatment[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2005, 32(5): 275-281. DOI: 10.3969/j.issn.1000-8179.2005.05.010

甲状腺微小癌的早期诊断和治疗(附34例临床分析)

Thyroid Microcarcinoma: the Early-stage Diagnosis and Treatment

  • 摘要: 目的 :探讨B超、FNA、术中冰冻切片在甲状腺微小癌TMC的早期诊断和治疗中的意义. 方法 :分析1992年~1998年经手术和病理证实的甲状腺微小癌34例的临床资料. 结果 :术前拟诊32例,B超诊断阳性率94.4%(32/34),FNA诊断阳性率81.1%,冰冻切片诊断阳性率90%,术后病理检查确诊微小癌34例,其中术中冰冻切片未发现3例,4例作患侧甲状腺叶加对侧甲状腺次全切除和双侧甲状腺次全切除术,28例行患侧甲状腺叶切除术:2例患侧甲状腺叶切除加改良性颈淋巴结清扫术,随访率88%(30/34),随访时间5~10年;1例对侧复发,无一例死亡. 结论 :B超结合FNA、术中冰冻检查能提高甲状腺微小癌的临床诊断率,有临床价值.甲状腺叶或次全切除治疗微小癌具有较好的疗效.

     

    Abstract: Objective :To evaluate ultrasonography,FNA and intraoperative freezing section as the early-stage diagnostic and treatment means of thyroid microcarcinoma (TMC). Methods :Clinical diagnosis and therapeutic data for 34 cases of postoperated patients with TMC confirmed by pathology in the period from 1992 1998 were analyzed. Results : Diagnostic positive rates by section were 94.4%(32/34), 81.1% and 90%, respectively in 32 csesultrasonography, diagnosed preoperatively. Through postoperative pathologic exam, 34 cases were confirmed as TMC that was not discovered in 3 cases by intraoperative freezing section. Near total thyroidectomy was performed in 4 cases, obectomy of cases. lobe in 28 cases, combined with cervical lymph node dissection were adopted in 2 Follow-up rate was 88%(30/34) with time ranging from 5 years to 11 years. One casepurred on opposite side and without mortality. Conclusions :Ultrasonography in combination with anon and intraoperative freezing section will help to increase the diagnostic rate, so FNA before operit has the value of clinical use. Total or near-total lobectomy fulfils the eradication of TMC.

     

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